EPL GW21 Predicted Line-ups & Score Predictions

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GW21 comes just two days after GW20 where, as predicted, goals returned (32 in total!) and 5 days after the end of GW19. This makes it one of the most rotation-sensitive rounds of the season. Rather than wholesale changes, managers are expected to manage minutes carefully — particularly for wide attackers, full-backs and players returning from injury. Arsenal and Liverpool likely to put full strength sides out in their match.

In this article we focus on the 5 clubs at the top of the table: Arsenal, Aston Villa, Chelsea, Liverpool and Manchester City. All predicted line-ups below are based strictly on GW19 and GW20 matchday squads, adjusted for injuries and short turnaround.

Don’t forget, the deadline for Gameweek 21 is set at 18:30 (UK time) on Tuesday, 6th January 2026. The free to play FPL or pay to play season/weekend/daily games like FanTeam are ideal ways of following the Premier League action.

🔴 Arsenal – Predicted XI (4-3-3)

Raya (95%)
Timber (85%) – Saliba (95%) – Gabriel (95%) – Hincapié (80%)
Zubimendi (85%)
Ødegaard (90%) – Rice (90%)
Saka (85%) – Gyökeres (80%) – Martinelli (80%)

FPL minutes

  • ✅ Safe: Raya, Saliba, Gabriel, Rice, Ødegaard
  • ⚠️ Rotation risk: Saka, Martinelli, Gyökeres but the Liverpool match is crucial.

🟣 Aston Villa – Predicted XI (4-2-3-1)

Martínez (95%)
Cash (85%) – Konsa (95%) – Lindelöf (90%) – Maatsen (85%)
Kamara (90%) – Tielemans (85%)
Rogers (80%) – McGinn (90%) – Buendía (85%)
Watkins (95%)

FPL minutes

  • ✅ Safe: Martínez, Konsa, McGinn, Watkins
  • ⚠️ Rotation risk: Rogers, Tielemans, Maatsen

🔵 Chelsea – Predicted XI (4-2-3-1)

Jørgensen (90%) (if Sanchez still injured)
Reece James (80%) – Chalobah (90%) – Badiashile (85%) – Gusto (85%) (if Cucurella still out)
Caicedo (90%) – Enzo Fernández (95%)
Palmer (95%) – João Pedro (85%) – Neto (80%)
Delap (80%)

FPL minutes

  • ✅ Safe: Palmer, Enzo
  • ⚠️ Rotation risk: James, João Pedro, Neto, Delap with Garnacho, Gittens & Estevao ready to come in

🔴 Liverpool – Predicted XI (4-2-3-1)

Alisson (95%)
Frimpong (85%) – Konaté (90%) – Van Dijk (95%) – Robertson (85%)
Mac Allister (90%) – Gravenberch (85%)
Szoboszlai (90%) – Wirtz (85%) – Gakpo (90%)
Ekitike (75%)

FPL minutes

  • ✅ Safe: Alisson, Van Dijk, Gakpo
  • ⚠️ Rotation risk: Robertson, Gravenberch but the Arsenal match is crucial.

🔵 Manchester City – Predicted XI (4-3-3)

Donnarumma (95%)
Nunes (85%) – Aké (90%) – Khusanov (80%) – O’Reilly (80%)
Rico Lewis (85%)
Reijnders (90%) – Foden (90%)
Bernardo Silva (95%) – Haaland (95%) – Doku (80%)

FPL minutes

  • ✅ Safe: Haaland, Bernardo, Foden
  • ⚠️ Rotation risk: Doku, Lewis (for Rodri who’s only just back from lang-term injury), O’Reilly
  • City down to last CBs if Dias ruled out (50% chance) with Gvardiol out with a tibial fracture. City bench will have some youngsters on it!

🔮 GW21 Score Predictions

FixturePrediction
Crystal Palace vs Aston Villa1–2 Aston Villa
Fulham vs Chelsea1–1 Draw
Manchester City vs Brighton3–1 Man City
Arsenal vs Liverpool2–2 Draw

🧠 GW21 FPL Summary

Safest captain options

  • Haaland
  • Watkins

High-upside but minutes risk

  • Saka
  • Doku
  • João Pedro

For further discussions have a look at FISO’s FPL forum where you can also see the FPL mini-leagues and FPL side-games available.