I brought Edurdo into my ISO team a while back, only for him to get injured in the first game and miss four weeks.
Since he came back he hasn't done anything as of yet, so although in theory he's a good pick, until this bears fruition in practice then it's hard to recommend him.
Fabregas is a great pick for now, but he usually starts off like a house on fire and then completely dries up in winter. Thought Arshavin was a sure-fire bet at the start of the season, but he's flattered to deceive too. Don't fancy any of the other Arsenal players.
Also, if you have Lampard and Gerrard then it's quite tricky to squeeze Fabregas in. Ideally, you could do Lampard

Fabregas and RVP

Drogba, but that pesky African Nations Cup gets in the way.
Left RVP in one team last week, with the idea of doing RVP

Torres when fit, but that's starting to look risky....